General information

Tetramizole: instructions for use in veterinary medicine


The granules contain 10% d1-2,3,5,6-tetra-hydro 6-phenyl-imidazo (2,1-b) thiazole hydrochloride.

Tetramizole is a broad-spectrum anthelmintic agent. It is used to prevent gastrointestinal and pulmonary nematodoses in ruminants and pigs. Effective against all major gastrointestinal and pulmonary nematodes. The drug simultaneously destroys almost all mature and immature forms of parasites. Due to the low toxicity and breadth of the therapeutic spectrum, there is practically no danger of developing toxic reactions in case of drug overdose.

The drug has a rapid effect, and is also rapidly inactivated and excreted from the body, so its effect ceases two days after taking the last dose. In animals invaded by pulmonary nematodes, already after 15-20 minutes after the use of tetramisole, cough increases, which ceases during the next day. Tetramisole only destroys pulmonary parasites, but does not cure the organic disturbances caused by them. Diarrhea caused by invasion of gastrointestinal parasites, passes in two days. Animals receiving the drug quickly recover due to increased appetite and better absorption of food. In therapeutic doses, tetramisole does not cause any side effects. Animals tolerate the drug even in doses several times higher than therapeutic. Tetramizole does not adversely affect young animals, or weakened and pregnant animals.

Invasions of gastrointestinal parasites: cattle: Dictycaulus viviparus, Haemonchus spp., Ostertagia spp., Trichostrongilus spp., Cooperia spp., Nematodirus spp., Oesophagostonum spp., Bunostonum phlebotonum, Chaethe-de-marte 2015, martyr. Opp. Dictycaulus filaria, Haemonchus, St. Petersburg, St. Petersburg, South Africa.

Dosage and administration.

Granules set with drinking water.

The granules are dissolved in water and given to ruminants through a probe or from a bottle. The dose is 1.5 g of granules per 10 kg of live weight, but not more than 45 g per head. Youngsters (lambs) weighing less than 10 kg give 1 g of granules.

To successfully combat parasite infestations, tetramisole should be used several times a year. Young cattle tetramisole is given 6-8 weeks after entering the pasture, but not later than July. In areas of increased risk of infection, prevention is repeated after a month. As a rule, cattle is treated with tetramisole.
in late autumn, after which the herds are distilled to new pastures or indoors.

For pregnant animals (sheep), the drug is given 4-6 weeks before lambing, and then during the weaning of lambs. The rest of the sheep - during gathering in the flock. The drug is given to the whole new flock of flocks. Tetramisole is given to lambs before weaning from the uterus, and in areas where mortality is high due to nematodoses, tetramisole is given to all lambs, from 4 months of age, every three months, until the threat of infection is eliminated. In the autumn period, tetramisole is given to the entire population of sheep. At the first signs of diarrhea or cough, cattle and sheep should be given tetramisole and animals should be transferred to new pastures. A single application, as a rule, is sufficient, but if necessary, repeat the treatment.

For group treatment of pigs, granules are used, which are mixed with feed in the proportion of 1.5 g / 10 kg of live weight. The granules are thoroughly mixed with the feed until a homogeneous mixture is obtained and set with the first daily ration in an amount that pigs can eat during the first hour. If water is needed to prepare the feed, it is added in the required amount to the finished mixture.

Method of treatment of pigs:

1. Piglets fed together should be about the same weight and have enough space at the trough with food.

Weakened piglets are fed separately, so that they receive a sufficient amount of the drug.

Pregnant sows are dewormed three weeks before farrowing. After applying the drug, animals are washed to remove parasite eggs from the skin, and transferred to clean rooms.

Two weeks after farrowing, the sows, along with the milk pigs, are transferred to clean rooms.

Due to the fact that the larvae and eggs of parasites can survive both indoors and on the soil, the remnants of feces, blood, pus and other physiological pollution should be destroyed.

6. When grazing pigs, they should be transferred to new pastures.

at a specific time.

Terms of rejection (residual concentrations).

Milk of treated animals is unsuitable for human consumption within 24 hours after deworming with tetramisole. Slaughter of animals for meat is not allowed within 7 days after the last treatment with tetramisole.

The composition of the drug

The main active ingredient of this tool is tetramisole hydrochloride. Besides him, the composition of the drug does not include any more active substances. Tetramisole hydrochloride is simply mixed with the filler in the manufacture of the drug. Externally, the drug is a powder, the color of which can vary from pure white to yellowish gray. Depending on the ratio of the active substance and the filler, Tetramisol is distinguished 20%, 10%, 5%, etc.

Operating principle

Getting into the body of the parasite, "Tetramizole", the instructions for use in veterinary medicine which will be discussed in detail below, enhances the activity of its central nervous system and simultaneously blocks the action of succinate and fumarate reductase. All this causes paralysis and death of the worm.

Who can use

Apply this tool is allowed for cattle, and for small. In addition, used for rabbits, horses, turkeys, chickens, pigs, etc. "Tetramizol." Instructions for use in veterinary medicine to piglets also give him permission. Use this drug is allowed no later than 7 days before slaughter of livestock or poultry. Milk of cows and eggs of chickens should not be eaten for 4 days after ingestion of medicines or chickens by animals.

Indications for use

The remedy has the best effect in full compliance with the instructions for the treatment of a worm infection.

The anthelmintic drug can be used both as a prophylactic measure and to combat the following diseases:

  • ascariasis
  • cooperative disease
  • hemonhoz
  • heterocidosis,
  • dictyocaulosis, etc.

As can be seen from the enumeration, tetramisole treats many helminthic invasions.

Before using the drug does not need a starvation diet, as well as the use of laxatives. Tetramisole is given once, it can be given by mouth to one animal or to a group with morning feeds, observing the following doses:

Dosing and Administration

Before using Tetramisole, there is no need to carry out any preparation, which is usually referred to as diet and bowel cleansing. Therapy is prescribed once, the medicine is given to the animals along with the morning meal. In the treatment of individuals, an injection of Tetramisole solution is used with a syringe without a needle directly into the bird's beak or the mouth of an animal.

The permissible dosage for birds is calculated independently based on the fact that 20 mg of Tetramisole is needed for each kg of animal or bird weight. For mass deworming, the required dose of the drug is mixed with food - 100 g of the mixture per individual. It is advisable to pre-test the drug on individual birds, if no negative effects are observed for 3 days, you can administer Tetramisole in large quantities.

Important! When carrying out treatment it is necessary to disinfect the chicken coops, in order to avoid re-infection.

Large and small horned livestock is drunk with medicine using a probe or a simple bottle. It will take 1.5 grams of tetramisole for every 10 kg of weight. For group use of the drug is taken the required number of granules, mixed with food and water to be eaten within an hour. This method is valid for animals of approximately the same weight.

Contraindications and possible side effects

Strict compliance with the instructions for use does not lead to overdose and the appearance of any side effects. Even a tenfold excess of the dose of Tetramisole did not reveal any negative effects. In very rare cases, allergic reactions are possible. However, there are cautions to using Tetramisole due to the following factors:

  1. Infectious diseases of any etiology.
  2. Liver and kidney damage.
  3. Exhaustion and hypotrophy of the body.
  4. Concurrent use of Tetramisole with other anthelmintics containing phosphorus and organic matter.
  5. Individual intolerance.

In the treatment of parasites, prevention is also important! Tetramizole is perfect for this purpose, it is allowed from 4 weeks of age for lambs and piglets. The instructions for use clearly spelled out the timing of the introduction of the drug for pregnant females, queens and pups. This is done once, with the identification of the disease - again. However, the most important precautionary measures also include the sanitation of premises and the hygiene of the animals themselves. Be attentive to them, and such troubles as helminthiasis and nematodoses, can be easily avoided.

Indications for use of the drug

To achieve the maximum effect from the use of "Tetramisol", one should strictly follow the instructions in the treatment of a particular disease.

The drug is used to treat diseases of poultry: chickens, geese, ducks, turkeys.

Anthelmintic agent is suitable for the treatment and prevention of such diseases:

  • dictiocaulosis,
  • hemonhoza,
  • bunostomosis,
  • nematodirosis,
  • ostetagia,
  • habertiosis,
  • cooperative disease
  • strongyloidiasis
  • ascariasis
  • esophagostomosis,
  • strongyloidiasis
  • trichuriasis,
  • metastrongylosis,
  • capillariasis
  • Heterokiasis,
  • amidostomy
  • syngamosis.

That is, the medicinal composition "Tetramizol" is suitable for the treatment of animals from a large number of diseases that are caused by worms.

For whom is suitable

"Tetramisol", following the instructions for its use, is suitable for the treatment of pigs, cattle and small cattle, poultry and sheep. Important!When using the specified composition for other animals, consult with a veterinarian beforehand.

Dosage and method of use for animals

Granules "Tetramizol" give the specified categories of animals in the morning time of the day without any additional preparations. Drug administration is made through the oral cavity, that is, it is used together with food or water.

Important!The described composition is used once, additionally giving it to animals to “enhance” the effect is prohibited, since the active substance belongs to moderately toxic compounds."Tetramizol" 10% has the following instructions for use: the substance is diluted in water and given to livestock by injecting the contents into the pharynx with a syringe or other medicine infusion device.

Before mass application for a large number of animals, should be tested on 5 individuals. Such actions are due to the fact that the drug can give complications due to low immunity in animals or conflict with other drugs (including antibiotics).

"Tetramizol" 10% dose for pigs: per 1 kg of weight give 100 mg of the drug. However, it is worth remembering that regardless of the mass of the pig, the maximum dose per animal is 45 g. Excess dosage leads to unpredictable consequences. For group treatment of pigs, the substance can be added to feed at the rate of 1.5 g per 10 kg of live weight. The quantity of feed should be such that the livestock can consume it in 1 hour.

Growing pigs at home is important to know the characteristics of their breeding, feeding and slaughter, as well as what breeds give more meat.

10% solution is used for the treatment of cattle in such doses: per 1 kg of live weight give 80 mg of the composition. If you use the drug for young animals, then it should be given in 1.5-2 months after entering the pasture. Adult cattle are usually treated in the autumn, before moving to a new pasture or in closed premises. "Tetramizol" 10% dosage for poultry: per 1 kg of live weight take 200 mg of the drug. It is impossible to give medicine with feed, only infusion with a syringe.

For sheep, 10% of the composition is used in the following dosage: per 1 kg of weight give 75 mg of the drug.

It is worth noting that the dosage is NOT indicated for the pure substance, but for the drug (remember that the pure substance in the medicine is 10%).

As stated above, "Tetramisol" is available in two forms: 10% and 20%, but the instructions for use are identical, as in the case of a 20 percent composition, all the above doses are divided by 2.

Important!Using the described drug for the treatment of livestock, which gives milk, products should be poured after milk yields during the day. It is allowed to kill animals only a week after taking the drug.

Side effects and contraindications

Applying "Tetramizol" in these doses side effects are not observed. However, it should not be given to animals that are sick with infectious diseases, in the last third of pregnancy, if the liver and kidneys are not functioning properly. Also, the drug is forbidden to use simultaneously with other anthelmintic compounds ("Pirantel", "Morantel"), as well as with any organophosphorus compounds.

By minor contraindications can be attributed to the application to some other groups of animals (dogs, cats, horses, etc.). For example, "Tetramizol", according to the instructions, is not used to treat rabbits, therefore, it is impossible to find the dosage and properly treat the animals.

Terms and conditions of storage

Store the drug should be in a dry place, away from sunlight. The maximum allowable temperature at the storage location is +30 ˚С. Shelf life - 5 years.

Did you know?Scientists have shown that roundworms live very close to the center of the Earth. Now you know how to use "Tetramizol" according to the instructions for which animals the drug is suitable (pigs, cattle, birds, sheep) and what possible side effects may occur after consuming this drug.